This study assesses the impact of climate change on pearl millet production in Niger using the CERES-Millet model within the DSSAT framework. Simulations under three climate scenarios (SSP1-2.6, SSP3-7.0, SSP5-8.5) and five Global Circulation Models project changes over three time periods (2015-2044, 2045-2074, 2075-2100). Model calibration and validation with field data confirm its reliability