Logo Lanfrica
  • Accueil
  • Atlas
  • Analyses
  • Documentation
  • Sign in

© 2026 Lanfrica. Tous droits réservés. Tous les droits d'auteur des ressources affichées sur le site Web Lanfrica appartiennent aux détenteurs de droits d'auteur d'origine, sauf indication contraire explicite.

DataSheet1_An Evolutionary Insight Into the Heterogeneous Severity Pattern of the SARS-CoV-2 Infection.PDF

Domaine:

healthcare

Type de record:

dataset
Créateur:
RabSum
Hôte:avatar

The ongoing pandemic of COVID-19 has elaborated an idiosyncratic pattern of SARS-CoV-2-induced symptoms in the human host. Some populations have succumbed to the SARS-CoV-2 infection in large numbers during this pandemic, whereas others have shown a resilient side by manifesting only milder or no symptoms at all. This observation has relayed the onus of the heterogeneous pattern of SARS-CoV-2-induced critical illness among different populations to the host genetic factors. Here, the evolutionary route was explored and three genetic loci, i.e., rs10735079, rs2109069, and rs2236757, associated with COVID-19 were analyzed. Among the three, the risk allele A at genetic locus rs2236757 residing in the IFNAR2 gene was observed to have undergone recent positive selection in the African population.

Visit

figshare.com

Tags

GeneticsGenetic EngineeringBiomarkersDevelopmental Genetics (incl. Sex Determination)Epigenetics (incl. Genome Methylation and Epigenomics)Gene Expression (incl. Microarray and other genome-wide approaches)Genome Structure and RegulationGenomicsGenetically Modified AnimalsLivestock Cloning+6

Licenses

CC BY 4.0

Similaires

Comparison of SARS-Cov-2 omicron variant with the previously identified SARS-Cov-2 variants in Egypt, 2020–2022: insight into SARS-Cov-2 genome evolution and its impact on epidemiology, clinical picture, disease severity, and mortalitySARS-CoV-2 Molecular Evolutionary Dynamics in the Greater Accra Region, GhanaPredicting the evolutionary and epidemiological dynamics of SARS-CoV-2 in South AfricaEarly assessment of the clinical severity of the SARS-CoV-2 Omicron variant in South AfricaEpidemiological drivers of transmissibility and severity of SARS-CoV-2 in EnglandThe Algerian chapter of SARS-CoV-2 pandemic: An evolutionary, genetic, and epidemiological prospect of the first wave

Comparison of SARS-Cov-2 omicron variant with the previously identified SARS-Cov-2 variants in Egypt, 2020–2022: insight into SARS-Cov-2 genome evolution and its impact on epidemiology, clinical picture, disease severity, and mortality

Abstract Background The o severe acute respiratory coronavirus 2 (SARS-CoV-2) pandemic has killed mi

SARS-CoV-2 Molecular Evolutionary Dynamics in the Greater Accra Region, Ghana

Predicting the evolutionary and epidemiological dynamics of SARS-CoV-2 in South Africa

Since the outbreak of coronavirus disease 2019 (COVID-19), the severe acute respiratory syndrome

Early assessment of the clinical severity of the SARS-CoV-2 Omicron variant in South Africa

ABSTRACT Background The SARS-CoV-2 Omicron

Epidemiological drivers of transmissibility and severity of SARS-CoV-2 in England

OBJECTIVES: Pandemic response in low-income countries (LICs) or settings often suffers from scarce e

The Algerian chapter of SARS-CoV-2 pandemic: An evolutionary, genetic, and epidemiological prospect of the first wave

Abstract To explore the SARS-CoV-2 early pandemic in Algeria, a