This study maps the existing body of literature on disability activism in Africa. It highlights and discusses key themes and debates, exposes research gaps, and recommends potential future directions for disability activism scholarship in Africa. The thematic review focuses on the post-Cold War era, from the early 1990s to the present, capturing the defining decade of the disability rights movement, which has been greatly influenced by legislation such as the 1990 Americans with Disabilities Act (ADA), the subsequent ADA Amendments Act (2008), and the 2008 United Nations Convention on the Rights of Persons with Disabilities. These are considered the movement's greatest legal achievements with global effects. In seeking to answer questions about changes and continuities in disability activism scholarship in Africa, the study found a shift towards decolonial scholarship. This supports the broader advocacy for decoloniality, spearheaded by scholarship aligned with the epistemologies of the Global South. The article argues that scholarship on disability activism can be further enriched by deliberately integrating African Indigenous Knowledge Systems.