Mycoplasma mycoides
subsp.
mycoides
is the etiological agent of contagious bovine pleuropneumonia (CBPP). While several findings on CBPP prevalence in Nigeria were documented, no data were reported about the genomic characterization of Nigerian
M. mycoides
subsp.
mycoides
strains. Here, we present the draft genome sequences of two novel
M. mycoides
subsp.
mycoides
strains isolated in Nigeria.