Background: Hypertension is the major modifiable risk factor for cardiovascular diseases that recently increased in Egypt and African regions has the highest prevalence of hypertension which can be controlled by self-care. The aim of the study was to determine the effect of belief, attitude, subjective norm, and enabling factors (BASNEF) model on knowledge and self-care behaviours for hypertensive patients. Methods: A quasi-experimental design was conducted for this study (experimental /control group). Setting: The study was conducted at Damanhur University Hospital, Egypt. Sample: A purposive sample of 100 patients with hypertension was divided randomly and assigned into two groups (50 intervention groups and 50 control groups) from the beginning of September 2021 to the end of February 2022. Tools: two tools were used for data collection, tool I: A structured questionnaire designed based on the BASNEF model components. Tool II: checklist about patient's self-control behaviors concerning blood pressure control. Results: The mean total scores of all BASNEF Model components were significantly improved post-intervention in the experimental group compared to the control group (P < 0.001).