This chapter attempts a philosophical exploration of the transformative potential of Artificial Intelligence (AI) in reimagining Nigeria’s management practices and social sciences. As AI continues to revolutionize industries worldwide, it presents unique opportunities and challenges for Nigeria’s socio-economic development, management practices and social sciences research. Drawing on Technological Determinism, Human-Centered AI, and Critical Social Theory, this chapter provides a comprehensive analysis of how AI can be integrated into Nigeria’s public and private sectors, with a focus on the ethical, socio-economic, and governance implications. The research design combines a theoretical framework with qualitative insights, employing secondary data to examine AI’s potential impact on management practices and the social sciences. The paper critiques the ethical concerns surrounding AI adoption, particularly issues of data privacy, algorithmic bias, and the digital divide while advocating for a balanced, inclusive, and ethical approach to AI integration. Key recommendations for policymakers include fostering inclusive AI education, promoting equitable access to AI technologies, and ensuring that AI systems are designed to serve the public good.