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Filovirus Glycoprotein Sequence, Structure and Virulence

Domaine:

healthcare

Type de record:

paper
Créateur:
Phillips, J C
Hôte:avatar
Leading Ebola subtypes exhibit a wide mortality range, here explained at the molecular level by using fractal hydropathic scaling of amino acid sequences based on protein self-organized criticality. Specific hydrophobic features in the hydrophilic mucin-like domain suffice to account for the wide mortality range. Significance statement: Ebola virus is spreading rapidly in Africa. The connection between protein amino acid sequence and mortality is identified here.

Visit

arxiv.org

Tags

Biomolecules

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