AnnabelleEN/Cholera-in-Zambia

# Comparison of Dose Vaccination regimes for Cholera in Zambia ## About Study The Guardian recently reported on the emergence of cholera – the very disease that made John Snow a pioneer of epidemiology. In that report, it is mentioned that in Zambia, for financial reasons, the standard two-dose oral vaccination regimen is stretched to single-dose vaccinations. This is done also due to evidence that a single dose provides “some” protection and can help contain outbreaks. ### Research Question The purpose of the study conducted at a local hospital was to determine if a single-dose cholera vaccination is as effective as the two-dose regimen to prevent admission to a hospital’s emergency room (ER). ### About Dataset The data are in a CSV file called CHOLERA.csv. It contains data collected among patients in the local hospital. These patients have been vaccinated over the last year and have recently come back with a diagnosis of cholera. Some of these patients needed emergency care and were admitted to the ER, while others were treated ambulatory. The age of the patients at vaccination was also recorded. The variables are: ID – patient id number ranging from 1 to 142 ER – admitted to ER: 1 = yes, 0 = no VAC – vaccination regimen: 1 = single-dose, 2 = two-dose Age – age in years ## Investigating Cholera Vaccination Data ```{r} # Loading Packages library(ggplot2) ``` ### Importing Dataset The dataset is in a CSV file, so I will be using the read.csv() function to import the dataset. ```{r} # import the data cholera Most of the patients in this study are around 30-60 years of age. The average age, as well as the youngest and oldest patient, can be found using the following functions: ```{r} summary(cholera$AGE) ``` The average age of patients in this study is 43 years old. The youngest patient is 3 years old, and the oldest patient is 92 years of age. Therefore, most participants in this study are indeed middle-aged. There is also a large range in age in t …