CatherineWenger/RotavirusCEA-Malawi

# Cost-effectiveness Analysis of Alternative Infant and Neonatal Rotavirus Vaccination Schedules in Malawi This repo contains the codes for the **PLoS GPH Publication:** Wenger C, Asare EO, Kwon J, Li X, Mwinjiwa E, et al. (2025) Cost-effectiveness analysis of alternative infant and neonatal rotavirus vaccination schedules in Malawi. PLOS Global Public Health 5(4): e0004341. This study compares the cost-effectiveness of 5 rotavirus vaccine strategies in Malawi from 2025-2034. #### Vaccine strategies: #### 1. No vaccination #### 2. Rotarix 2-dose schedule (administered at 6 and 10 weeks) #### 3. Rotarix 3-dose schedule (administered at 6, 10, and 14 weeks) #### 4. Rotarix 3-dose schedule (administered at 6, 10, and 40 weeks) #### 5. Next-generation neonatal (RV3-BB) 3-dose schedule (administered at 1, 6, and 10, weeks) These strategies were evaluated from the government and societal perspectives. ICERs were calculated and cost-effectiveness was also evaluated using the net-benefit framework. ## File descriptions TDMdata.Rdata contains the simulated epidemiological data generated using the model in Pitzer et al. 2024). It includes the yearly number of moderate-to-severe and non-severe cases for 5 age groups (