Project Oracle: metagenomics of agricultural soils from Burkina Faso
# Project Oracle
## Metagenomics of agricultural soils from Burkina Faso
### Sampling and sample processing
- Sample collection (2017),
- geographical coordinates,
- DNA extraction,
- Shotgun sequencing (Illumina NovaSeq),
- 16S and ITS2 amplification and sequencing (Illumina MiSeq)
(to be written)
### From raw sequences to annotated occurrence tables
(scripts are available, will be added later)
### Statistical analysis
(see the Rmarkdown scripts, starting with
src/04\_numerical\_ecology.Rmd)
Note that library functions are noted as `package::function()` (for
example, `vegan::diversity()`), except for tidyverse functions and
base packages.
#### Taxonomy
temporary code to extract and prepare the Silva taxonomy:
```sh
cd ./data/Silva/
zgrep "^>" SILVA_138.1_SSURef_NR99_tax_silva.fasta.gz | \
sed 's/^>// ; s/ /\t/1' > SILVA_138.1_SSURef_NR99_tax_silva.txt
```
**Roadmap (16S)**:
- [x] metabarcoding: decontamination and filtering,
- [x] metabarcoding: alpha diversity,
- [x] metabarcoding: alpha diversity vs locality,
- [x] metabarcoding: beta diversity vs locality,
- [x] metabarcoding: beta diversity vs locality (make a new plot with
barycenters),
- [x] metabarcoding: use 20 taxonomic fields and weighted assignments,
- [ ] metabarcoding: taxonomy and functions (nitrogen cycle),
- [x] metagenomics shotgun: filtering,
- [ ] metagenomics shotgun: turn NMDS plot into a function,
- [ ] metagenomics shotgun: use the metabarcoding taxonomic framework,
- [ ] metagenomics shotgun: alpha diversity,
- [ ] metagenomics shotgun: alpha diversity vs locality,
- [ ] metagenomics shotgun: beta diversity vs locality,