mahmood726-cyber/hiv-e156

E156 micro-paper, protocol, and data scaffold for lean Africa-site HIV RCT transfer patterns # Lean Africa-site HIV RCTs as a transfer template This repository packages a local E156 micro-paper, protocol draft, data extracts, and reproducibility files for a registry-first scan of Africa-site randomized trials. ## Research Question The primary descriptive question is how often Africa-site trials in this topic meet a pragmatic shortlist for cheaper and faster delivery. ## Current Result - Africa benchmark trials: `80` - Transfer shortlist trials: `18` - Shortlist proportion: `0.23` with Wilson 95% interval `0.15` to `0.33` - Median trial duration days: `824.5` - Median results-reporting lag days: `566.5` - Most represented Africa-site countries: South Africa (41), Uganda (21), Kenya (21), Malawi (9), Zimbabwe (8) ## Release Track - Active paper format: `E156 micro-paper` - Active paper body: exactly `156` words, `7` sentences, single paragraph - Conventional journal expansion is deferred unless explicitly requested ## Layout - `paper/`: E156 body, article JSON, validation record, and HTML bundle - `protocol/`: submission-oriented protocol draft - `data/`: copied topic outputs from the parent analysis project - `code/`: local scripts needed to rerun validation and rebuild the bundle - `.github/workflows/`: lightweight validation workflow for GitHub-hosted use - `submission/`: E156-facing manuscript wrapper, title metadata, note files, and expansion notes - `STATUS.md`: current completion state and remaining gaps ## Quick Start Validate the E156 body: ```bash python3 code/validate_e156.py --file paper/article.json --json-field body ``` Rebuild the HTML bundle: ```bash python3 code/build_e156_bundle.py --input paper/article.json --output paper/index.html --template templates/e156_interactive_template.html ``` ## Status - Local E156 body validated - Local HTML bundle generated - Protocol tightened beyond the initial skeleton - Local git repo initialized - Public GitHub repository is live at `github.com` - Active s …