proctor-ucsf/mordor-antibody

Analysis of multiplex antibody endpoints in the MORDOR Niger trial # mordor-antibody Analysis of multiplex antibody endpoints in the MORDOR Niger trial ## Description This repository includes R code to run all of the analysis for the paper: _Effect of biannual azithromycin distribution on antibody responses to malaria, bacterial, and protozoan pathogens in Niger_ Arzika, A. M., Maliki, R., Goodhew, E. B., Rogier, E., Priest, J. W., Lebas, E., O’Brien, K. S., Le, V., Oldenburg, C. E., Doan, T., Porco, T. C., Keenan, J. D., Lietman, T. M., Martin, D. L., Arnold, B. F. & MORDOR-Niger Study Group. _Nat. Commun._ 13, 976 (2022). pubmed.ncbi.nlm.nih.gov nature.com Should you have any questions about the files in this repository, please contact Ben Arnold at UCSF (ben.arnold@ucsf.edu). ## Linked Repositories and Additional Resources ### Open Science Framework This GitHub repository is mirrored on the Open Science Framework (OSF). The OSF project page includes additional study-related resources, including the pre-analysis plan, the datasets, and the compiled HTML computational notebooks created from the `.Rmd` files: osf.io ### Dryad The data have also been archived on Dryad: datadryad.org Arnold et al. (2021), Multiplex IgG antibody response and malaria parasitemia among children ages 1-59 months in the MORDOR Niger trial, 2015-2018, Dryad, Dataset, doi.org ## _Nature_ Research Code Submission Items Following: nature.com ### System Requirements All analyses were run using R software version 4.1.1 on Mac OSX Big Sur using the RStudio IDE (rstudio.com). `> sessionInfo()` `R version 4.1.1 (2021-08-10)` `Platform: x86_64-apple-darwin17.0 (64-bit)` `Running under: macOS Big Sur 11.6.1` ### Installation Guide You can download and install R from CRAN: cran.r-project.org You can download and install RStudio from their w …