Harmonized multi-modal medical imaging validation / test corpus and healthy-tissue reference statistics (chest X-ray, CT, brain MRI)

This dataset provides a harmonized, quality-controlled, multi-modal medical imaging corpus assembled from five public sources spanning three modalities: chest X-ray (NIH ChestX-ray14), CT (DeepLesion, LIDC-IDRI), and brain MRI (BraTS-Africa, OpenBHB). All images have been standardized to a consistent 2D schema (256x256, uint8) with unified metadata fields (patient ID, acquisition site, split), following dataset-specific quality-control procedures including DICOM series completeness/modality auditing, HU intensity-offset correction and clinical windowing for CT, and brain-tissue-occupancy slice filtering for volumetric MRI-to-2D conversion. Also included are precomputed healthy-tissue reference statistics (Sref_mri.npz, Sref_cxr.npz): mean and covariance of unsupervised tissue-composition ratios, computed from confirmed-healthy image subsets (NIH ChestX-ray14 No Finding cases; OpenBHB control subjects), intended as a plausibility baseline for anomaly detection and explainable generative modeling research. Due to file size, the corpus is split across two access points: validation and test partitions plus the Sref statistics are hosted directly in this repository; training partitions (~18GB combined) are provided via a direct external link, as file size exceeds this repository's storage limit. All partitions are additionally fully reproducible from the cited public source repositories using the processing pipeline documented in the accompanying Data in Brief article, which is the authoritative long-term reference for reproducibility. Files hosted in this repository (Mendeley Data): val.zip - validation partitions for all five datasets: chestxray14_val.h5 (chest X-ray, 14-class pathology labels), deeplesion_val.h5 (CT, lesion-type labels), brats2d_val.h5 (brain MRI, 4-channel T1n/T1c/T2f/T2w, tumor category labels), lidcidri2d_val.h5 (CT, lung-windowed), openbhb2d_val.h5 (brain MRI, 62 real acquisition sites, control diagnosis) test.zip - test partitions for the same five datasets, identical structure to val.zip sref.zip - Sref_mri.npz, Sref_cxr.npz: healthy-tissue reference statistics Files hosted via external link (not archival; see also Related Links): train.zip - training partitions for all five datasets: chestxray14_train.h5, deeplesion_train.h5, brats2d_train.h5, lidcidri2d_train.h5, openbhb2d_train.h5 Link: drive.google.com