Heat exposure and perinatal mortality: A time-stratified, case-crossover study from 16 hospitals in Benin, Malawi, Tanzania and Uganda

Domaine:

healthcareclimate

Créateur:

ClaJerKriMar

Éditeur:

Spr

Hôte:

Abstract Extreme heat events affect both pregnant women and their infants. We applied a time-stratified case-crossover design including 124,819 singleton births in a prospective observational study in 16 hospitals in Benin, Malawi, Tanzania, and Uganda to investigate the association between extreme heat and timing of perinatal death. We observed weak associations between heat exposure and perinatal mortality with an odds ratio of 1.22 (95%CI 0.85-1.73) for stillbirths; 1.10 (95%CI 0.51-2.34) for antepartum and 1.54 (95%CI 0.63-3.73) for intrapartum stillbirths; and 1.17 (95%CI 0.84-2.61) for perinatal deaths with an increase from 75 th to 99 th percentile in mean temperature one week (lag 0-6 days) before childbirth. The cumulative exposure-response curve suggested the steepest slope for heat was in intrapartum stillbirths, and stronger associations during the hottest seasons. We conclude that higher temperatures may have short-term effects on mortality risks, particularly for intrapartum stillbirths, raising the importance of improved intrapartum care.

Heat exposure and perinatal mortality: A time-stratified, case-crossover study from 16 hospitals in Benin, Malawi, Tanzania and Uganda التعرض للحرارة والوفيات في الفترة المحيطة بالولادة: دراسة متقاطعة للحالات من 16 مستشفى في بنين وملاوي وتنزانيا وأوغندا Exposition à la chaleur et mortalité périnatale : une étude de cas stratifiée dans le temps provenant de 16 hôpitaux au Bénin, au Malawi, en Tanzanie et en Ouganda Exposición al calor y mortalidad perinatal: un estudio cruzado de casos estratificado en el tiempo de 16 hospitales en Benin, Malawi, Tanzania y Uganda

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