Higher mortality associated with the SARS-CoV-2 Delta variant in the Western Cape, South Africa, using RdRp target delay as a proxy
Domaine:
healthcareType de record:
paper
Créateur:
Car
CarÉditeur:
ope
Hôte:
Abstract
A novel proxy for the Delta variant, RNA-dependent RNA polymerase target delay in the Seegene Allplex™ 2019-nCoV PCR assay, was associated with higher mortality (adjusted Odds Ratio 1.45 [95%CI 1.13-1.86]), compared to presumptive Beta infection, in the Western Cape, South Africa (April-July 2021). Prior diagnosed infection and vaccination were protective.
Similaires
New Variant of SARS-CoV-2 in South AfricaIdentification of SARS‐CoV‐2 Omicron variant using spike gene target failure and genotyping assays, Gauteng, South Africa, 2021Tracking the circulating SARS-CoV-2 variant of concern in South Africa using wastewater-based epidemiologyDetection of a SARS-CoV-2 variant of concern in South AfricaPhylogeography and genomic analysis of SARS-CoV-2 delta variant in MoroccoEarly assessment of the clinical severity of the SARS-CoV-2 Omicron variant in South Africa