Hypertension in Colombia: First pharmacogenomic risk profile stratified by ancestry

# htn-gwas ## Purpose This study explores the influence of genetic ancestry on PGx risk profile related to hypertension in Colombian populations. We assessed allele frequency differences between African- and European-ancestry groups and performed correlation analyses. This repository includes both the full dataset and analysis scripts, enabling full reproducibility of all results. ## Repository Structure - `main_analysis.R`: Main script with numbered and annotated sections for reproducibility.- `data/`: Filtered dataset used for statistical and graphical analyses.  - `Supplementary Material 1-2`: Full set of PGx and bibliometric data. ## How to Use 1. Clone or download this repository.2. Open `main_analysis.R` in RStudio.3. Ensure the files in the `data/` folder are correctly referenced.4. Install required R packages (see script).5. Run the script from beginning to end or explore specific numbered sections. ## Reproducibility > ✅ **This repository is fully reproducible**: All datasets and scripts are included, and no external data download is required. ## Citation If you use or adapt this code, please cite the associated article (once published) and acknowledge this repository. ## LicenseThis project is licensed under the **MIT License**. You are free to use, modify, and distribute the code with attribution.