Incidence of hepatitis E virus among elevated liver enzyme (ALT, AST) Sudanese patients, Khartoum, Sudan

Abstract Background Hepatitis E Virus (HEV) infection is a newly recognized serious threat to global public health and Africa is suspected to be among the most severely affected regions in the world. Objective This study aimed to detect the frequency of anti-hepatitis E IgM, among elevated liver enzyme patients. Methods The current study is descriptive cross-sectional study carried out between April to august 2016, Ninety Patients with high liver enzyme ALT&AST and non B non C hepatitis attended Ibn senaa hospital Khartoum north, Omdurman teaching hospital and bahri teaching hospital bahri north, sedan were collected and tested by using (ELISA) kit Results show that Out of the 90 samples tested in order to evaluate the effect of age on HEV seropositivity, there was a significant difference (P < 0.05) between HEV seropositivity and age group, Conclusion study demonstrates the high prevalence rate of HEV seropositivity among non-hepatitis patients with high level enzyme ALT, AST. This will raise the potential risk of HEV infection by blood transfusion and may be the source of the outbreak.