We present a dataset describing (i) crop locations, (ii) biophysical parameters and (iii) crop yield and biomass was collected in 2020 and 2021 in Ghana, mostly focusing on maize in northern Ghana. The dataset contains repeated multiple measurements of leaf area index (LAI), leaf chlorophyll concentration over a large number of maize fields, as well as associated grain yield, biomass and polygons that delineate the fields.