Logo Lanfrica
  • Accueil
  • Atlas
  • Analyses
  • Documentation
  • Sign in

© 2026 Lanfrica. Tous droits réservés. Tous les droits d'auteur des ressources affichées sur le site Web Lanfrica appartiennent aux détenteurs de droits d'auteur d'origine, sauf indication contraire explicite.

Maternal component in the familial aggregation of hypertension

Domaine:

healthcare
Créateur:
AL H GN HM B
Éditeur:
WILEY
Hôte:
To assess maternal versus paternal contributions to the familial aggregation of hypertension, we examined family history data from 344 hypertensive probands (69 African American, 153 US Caucasian, 122 Greek Caucasian) ascertained without respect to parental hypertension status. The proportion of hypertensive mothers (81.7, 65.0 and 84.8% for African Americans, US Caucasians and Greek Caucasians, respectively) of these probands was significantly greater than the proportion of hypertensive fathers (50.0, 44.9 and 48.3%, respectively) in all three ethnic groups. The lifetime risk of hypertension was significantly greater for mothers compared with fathers of these hypertensive probands (p<0.001). Examination of the proband's siblings indicated that maternal history of hypertension was associated with greater lifetime risk for hypertension than paternal history (p<0.01). In conclusion, we observe a consistent maternal component in the inheritance of hypertension. Although we cannot separate a maternal genetic from epigenetic or environmental effect, our findings suggest that genetic research should include studies of the mitochondrial as well as nuclear genome. Furthermore, when assessing a patient's risk for hypertension, particular attention should be paid to the maternal family history.

Visit

doi.org

Licenses

http://onlinelibrary.wiley.com/termsAndConditions#vor

Similaires

Blood Pressure Profile, Prevalence of Hypertension and Associated Familial Factors in School Children in Accra, GhanaCode for "Fatalism or vigilance? Familial death & subsequent use of maternal health services in Malawi"Social cognitive map of the Makay SES based on the aggregation of the 32 individual cognitive maps and represented at the level of component types for the sake of visibility.Maternal diets and dietary diversity in relation to pregnancy hypertension in sub-Saharan AfricaThe molecular basis and diagnosis of familial hypercholesterolaemia in South African AfrikanersTypologically Informed Parameter Aggregation

Blood Pressure Profile, Prevalence of Hypertension and Associated Familial Factors in School Children in Accra, Ghana

Background: Essential hypertension, which is hypertension without a known cause, runs

Code for "Fatalism or vigilance? Familial death & subsequent use of maternal health services in Malawi"

This is the code used for the first Revision and Resubmission of "Fatalism or vigilance? Familial de

Social cognitive map of the Makay SES based on the aggregation of the 32 individual cognitive maps and represented at the level of component types for the sake of visibility.

The central component zone contains components with high centrality scores, while the peripheral

Maternal diets and dietary diversity in relation to pregnancy hypertension in sub-Saharan Africa

Pre-eclampsia and other hypertensive disorders of pregnancy are the second leading cause of maternal

The molecular basis and diagnosis of familial hypercholesterolaemia in South African Afrikaners

SUMMARY Three different point mutations were recently identified in South African familial hypercho

Typologically Informed Parameter Aggregation

Massively multilingual language models enable cross-lingual generalization but underperform on low-r