glaucoma-gwas
Purpose
This study explores the influence of genetic ancestry on the genetic risk profile related to glaucoma in Colombian populations. We assessed allele frequency differences between African- and European-ancestry groups and performed correlation analyses.
This repository includes both the full dataset and analysis scripts, enabling full reproducibility of all results.
Repository Structure
Main_Analysis.R: Main script with numbered and annotated sections for reproducibility.
data/: Filtered dataset used for statistical and graphical analyses.
Supplementary Material 1-2: Full set of GWAS and bibliometric data.
How to Use
Clone or download this repository.
Open main_analysis.R in RStudio.
Ensure the files in the data/ folder are correctly referenced.
Install required R packages (see script).
Run the script from beginning to end or explore specific numbered sections.
Reproducibility
✅ This repository is fully reproducible: All datasets and scripts are included, and no external data download is required.
Citation
If you use or adapt this code, please cite the associated article (once published) and acknowledge this repository.
License
This project is licensed under the MIT License. You are free to use, modify, and distribute the code with attribution.