Intercropping, the practice of growing two or more crops together on the same plot of land. Intercropping has been widely promoted as a sustainable agricultural practice that enhances farm resilience, improves resource use efficiency, and potentially boosts household welfare. In Ghana, smallholder farmers face challenges such as climate variability, declining soil fertility, and fluctuating market prices. Intercropping is believed to mitigate these risks through diversification, improved soil health, and better resource utilization. However, empirical evidence on the impact of intercropping on farm resilience and household welfare is fragmented, with variations in methodology, context, and measurement indicators. A systematic literature review will synthesize available empirical findings, assess the methodological quality of existing studies, and identify key gaps for future research. This synthesis will provide policymakers, development practitioners, and researchers with a clearer understanding of the role of intercropping in sustainable agricultural development in Ghana.