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New Jersey Caucasian, African American, and Hispanic Population Data on the PCR-Based Loci HLA-DQA1, LDLR, GYPA, HBGG, D7S8, and Gc

Domaine:

healthcare
Créateur:
LB B BNT JA
Éditeur:
AST
Hôte:
Abstract New Jersey Caucasian, African American, and Hispanic genotype and allele frequencies were determined for the six PCR-based loci, HLA-DQA1, LDLR, GYPA, HBGG, D7S8, and Gc. All but one locus (HLA-DQA1 for African Americans) meet Hardy-Weinberg expectations. However, observing one departure in 18 loci over the three New Jersey sample populations is not unexpected. There is little evidence for departures from independence between pairs of loci in the three populations studied. Thus, multiple locus profile frequencies can be determined using the product rule.