<p>Conceptual framework of arboviral severity determinants in African populations.</p>

Viral, host immune and host genetic factors identified across the five arboviruses, with the modifying context of co-infection, surveillance and healthcare access, and their relation to the clinical severity outcomes recorded for each virus. The bar at the foot of the figure ranks the relative depth of the evidence base by virus. This figure is the original work of the authors, is published under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) licence, and has not been reproduced or adapted from any previously published source.