<p>Distributions of FEV1 adjusted for age and sex stratified by cluster.</p>

Vertical dotted lines represent the mean of the distribution. Cluster labels and colours match those in Fig 6a. Cluster 17 is mostly European-born individuals; Cluster 18 is mostly individuals born in African countries at or south of the equator; Cluster 19 is mostly individuals born in England, the Caribbean, Ghana, and Nigeria; and Cluster 22 is mostly individuals born in England who chose the EB “White and Black Caribbean” or “White and Black African”. (a) Top: Distribution of FEV1 by cluster without adjusting for population structure. (b) Bottom: Distribution of FEV1 by cluster after having adjusted for the top 40 PCs.

(JPEG)