Pharmacognostical, Phytochemical and In –vitro Evaluation of Ethanol extract of Abutilon guineense for Diabetic foot ulcer Activity

Diabetic foot ulcer is one of the most severe complications associated with Diabetes mellitus, leading to delayed wound healing and increased risk of infection. Medicinal plants play a significant role in the management of chronic wounds due to their bioactive phytoconstituents. Abutilon guineense a subspecies of Abutilon indicum belonging to the family Malvaceae, has been traditionally used for its wound healing and antidiabetic properties. The present study aims to investigate the Pharmacognostic and phytochemical characteristics and In vitro Pharmacological studies of Abutilon guineense with special emphasis on its wound healing activity in diabetic foot ulcer conditions. Preliminary Phytochemical screening revealed the presence of important secondary metabolites such as flavonoids, tannins, alkaloids, and other phenolic compounds which are known to promote tissue regeneration and wound contraction. In vitro evaluation using the ethanol extract of Abutilon guineense showed a significant activity in scratch assay model demonstrated significant wound healing potential, thereby supporting its traditional application in the treatment of diabetic wounds.