Pressure ulcers remain a major healthcare challenge among bedridden patients and are widely
recognized as indicators of quality nursing care and patient safety. Despite advances in preventive
nursing interventions, pressure ulcers continue to occur in healthcare institutions due to several
individual and institutional factors affecting nurses’ preventive practices. This study investigated
the predictors of pressure ulcer prevention practices among nurses caring for bedridden patients
across teaching hospitals in North-Central Nigeria. The study adopted a descriptive cross
sectional survey design. The population comprised registered nurses working in units caring for
bedridden patients in teaching hospitals across the zone, while a sample size of 147 nurses was
selected for the study. Data were collected using a structured questionnaire. The instrument was
validated by experts, while reliability was established using Cronbach Alpha reliability method
with an overall reliability coefficient of 0.82. Data collected were analyzed using descriptive and
inferential statistics with the aid of Statistical Package for Social Sciences (SPSS) version 27.
Findings revealed that nurses possessed good knowledge regarding pressure ulcer prevention and
demonstrated positive attitudes toward pressure ulcer prevention. The study further revealed that
nurses exhibited relatively good pressure ulcer prevention practices. Institutional and resource
related factors such as workload, staff shortage, inadequate nurse-patient ratio, and availability
of equipment significantly influenced preventive practices. The findings also showed significant
relationships between knowledge and prevention practices, institutional factors and prevention
practices, as well as attitudes and prevention practices. Multiple regression analysis revealed that
attitude was the strongest predictor of pressure ulcer prevention practices (46%), followed by
knowledge (41%) and institutional factors (33%), with all predictors contributing significantly to
the model (p < .001). The study concluded that effective pressure ulcer prevention among
bedridden patients depends on nurses’ knowledge, positive attitudes, and supportive institutional
environments. The study recommended continuous professional education, provision of pressure
relieving devices, improved staffing, and strengthening of institutional support systems to enhance
pressure ulcer prevention practices among nurses.