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Publication bias and time to publication of randomized trials in sub-Saharan Africa: A cross-sectional registry study

Domaine:

healthcare

Type de record:

dataset
Créateur:
ClaKredo, TamaraHohlor
Éditeur:
Cen
Éditeur:
OSF
Hôte:avatar
Purpose: Estimate (1) the proportion of completed/terminated SSA RCTs that are published and (2) the time from primary completion to journal publication. Design & data source: Cross-sectional study of RCTs registered in ClinicalTrials.gov and PACTR (registered ≥2010; primary completion < Jan 1, 2025; SSA site). Key outcomes: Publication status (journal article found/not found) and time-to-publication (months from primary completion to first journal publication). Key findings (headline): Of 3,026 eligible RCTs, 1,983 (65.5%) had a journal publication; median time-to-publication = 34.2 months (95% CI 32.4–35.5). Planned outputs: Descriptive tables; Kaplan–Meier curves overall and by subgroups (registry, recruitment status, age category, funding, single vs multi-country); policy-relevant recommendations to reduce non-/late publication.

Tags

Medicine and Health SciencesClinicalTrials.govPACTRclinical trial registrationpublication biasrandomized controlled trialsresearch wastesurvival analysis

Licenses

Creative Commons Attribution 4.0 Internationalhttps://creativecommons.org/licenses/by/4.0/legalcode

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