This dataset supports a retrospective microcosting analysis of a nationwide typhoid conjugate vaccine (TCV) campaign conducted in Burkina Faso in 2025. Data were collected across multiple administrative levels (national, regional, district, and health facility) and include information on resource use, unit costs, and vaccine delivery outputs. Costs were estimated from the government perspective using an ingredients-based approach and are reported as financial and economic costs in 2024 USD. Health facility and district identifiers have been anonymized to ensure confidentiality.