This study, conducted within the SteamBioAfrica project, assessed the potential of Digital Soil Mapping (DSM) to estimate Soil Organic Carbon (SOC) across key regions of southern Africa: Otjozondjupa and Omusati (Namibia), Chobe (Botswana), and KwaZulu-Natal (South Africa). Random Forest (RF) models were implemented in the Google Earth Engine (GEE) environment, integrating multi-source datasets including real-time Sentinel-2 imagery, topographic variables, climatic data, and regional soil samples. Three model configurations were evaluated: (A) climatic, topographic, and spectral data; (B) topographic and spectral data; and (C) spectral data only. Model A achieved the highest overall accuracy (R2 up to 0.78), particularly in Otjozondjupa, whereas Model B resulted in the lowest RMSE and MAE. Model C exhibited poorer performance, underscoring the importance of multi-source data integration. SOC variability was primarily influenced by elevation, precipitation, temperature, and Sentinel-2 bands B11 and B8. However, data scarcity and inconsistent sampling, especially in Chobe, reduced model reliability (R2: 0.62). The originality of this study lay in the scalable integration of real-time Sentinel-2 data with regional datasets in an open-access framework. The resulting SOC maps provided actionable insights for land-use planning and climate adaptation in savanna ecosystems.