Structural conservation between PNC homologues.

Alignment of sequences (A) and structures (B) of PNC homologues from P.horikoshii (yellow), A.baumanii (pink) and S.cerevisiae (blue). Although there is an increasing structural complexity from a monomer in Archaea, a dimer in Bacteria and an heptamer in Fungi and the amino acid identity of the sequences is around 30%, the 3D structural subunits of PNC homologues are superimposable.