Summary of Genetic Variations of SNPs in this Study.

a

data published on hapmap; b, data calculated in this study, N = 48; N/A, no data found in hapmap.

MAF: Minor Allele frequencies; CHB: Han Chinese in Beijing, China; ASW: African ancestry in Southwest USA; CEU: Utah residents with Northern and Western European ancestry from the CEPH collection ORM1, orosomucoid 1; ABCC2, ATP-binding cassette, sub-family C, member 2; ABCG2, ATP-binding cassette, sub-family G, member 2; ABCB1, ATP-binding cassette, sub-family B, member 1; SLCO1B3, solute carrier organic anion transporter family, member 1B3; SNP, single nucleotide polymorphisms; AUC_(0–48) the area under the plasma concentration-time curve (AUC) from 0 to 48 h; AUC_(0–∞), AUC from 0 to ∞; C_max, the peak concentration in plasma; CL/F, clearance; T_1/2, elimination half-life; T_max, the time to C_max.