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Supplementary Table ST3 from Expanding the Prostate Cancer Cell Line Repertoire with ACRJ-PC28, an AR-negative Neuroendocrine Cell Line Derived From an African-Caribbean Patient

Domaine:

healthcare

Type de record:

dataset
Créateur:
HenWilBelZir
Hôte:avatar

All Exonic Variants which are present in ACRJ-PC28. SIFT, Polyphen2, LRT, MutationTaster, MutationAssessor, and CADD were used to predict variant effect. Pop_Freq_max is the maximum population frequency of the variant in 1000Genome Project (Aug 2015), Exome Sequence Project (ESP6500) and Genome Aggregation Database (gnomAD). Total_Damaging represents number of times the variant was predicted as damaging by the 5 methods used. There are 605 variants that are predicted as damaging for 5 methods (green) while 296 variants are predicted as damaging for 4 out of 5 methods (orange-brown), among them is the variant in ATM (rs147934285) (dk brown). 3). Additionally, 539 variants are predicted as damaging for 3 out of 5 methods (blue-purple). The data generated and/or analyzed during the current study are available from the corresponding author on reasonable request.

Tags

CancerCancer BiologyTumor BiologyMethods and TechnologyCancer PreventionEpidemiologyGenitourinary CancersProstate cancerPreclinical ModelsIn vitro models of cancer+6

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CC BY

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