This project contains the prospectively registered protocol, supplementary materials, and supporting documentation for a systematic review that will identify, critically appraise, and synthesise national and international clinical practice guidelines relating to videofluoroscopic swallow studies (VFSS). The review constitutes Phase 1 of a doctoral study at the University of Cape Town aimed at adapting and contextualising an evidence-informed South African clinical practice guideline using the South African Guidelines Excellence (SAGE) framework