The role of Innovation on small and medium enterprises (SMEs) growth is inevitable in any form of business organisation. Innovation has to do with a new idea, creative thought, and new imaginations of device of production of new product to add value to its customer. Innovation save as rebirth of product and reintroduce product in new look. This study have assess the impact of investment and technological innovation in growth of SMEs in Yobe State Nigeria. Structured questionnaire were used to gather the data, random sampling method were also adopted in surveying the 150 number of respondent. The finding shows significant relationship between innovation of product and production device and small and medium Growth, the result shows there is a relationship and the relationship is medium and positive. Moreover therefore there is impact of both investment and technological innovation on small and medium enterprises Growth The innovation has highly increase the growth of the enterprises. The study also recommend the government to consider and increase funds being allocated to grow the SMEs to make more innovations.