Background:
Sub-Saharan Africa (SSA) bears 25% of the global disease burden, yet accounts for only 3% of the world's health
workforce [1]. Smartphone-dependent digital health platforms have failed to reach most rural populations in SSA, and the
2023 collapse of Babyl Rwanda demonstrated the structural fragility of externally owned digital health infrastructure [2].
Objective:
To evaluate the feasibility, acceptability, and 90-day user retention of HealthDrive, a USSD-based telehealth platform
with community health worker (CHW) integration, in a pilot study conducted in two rural SSA communities.
Methods:
A mixed-methods pilot implementation study (n=50 enrolled patients, 12 CHWs) conducted August 2024 to March
2026, applying the Consolidated Framework for Implementation Research (CFIR) [3], the Technology Acceptance Model
for Resource-Limited Settings (TAM-RLS) [4], and the RE-AIM evaluation framework [5]. USSD interaction logs (1,247
sessions across four short codes), CHW follow-up records, and structured satisfaction interviews were analysed.
Results:
Three-month user retention was 78% (95% CI: 64–88%), exceeding SSA mHealth benchmarks (45–65%). Elderly user
satisfaction reached 85%. Emergency triage sessions achieved 71% completion. Total platform expenditure was $2,580 over
19 months at $125/month.
Conclusions:
USSD-based telehealth with CHW integration is feasible and acceptable in rural SSA. Five open machine learning and
signal processing challenges are identified as critical barriers to scaling this model to population-scale voice-based health
triage.