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What Is Kisumu? Between-laboratory variability in the Anopheles gambiae Kisumu reference strain: anonymised data and analysis code

Domaine:

healthcare

Type de record:

dataset
Créateur:
PraHarWriLee
Éditeur:
AfrCenSwiIfa
Éditeur:
Zenodo
Hôte:avatar
Anonymised data and analysis code for a study of phenotypic insecticide-susceptibility variation in the Anopheles gambiae "Kisumu" reference strain held across sixteen laboratories. Colonies were tested against four insecticides (permethrin, alpha-cypermethrin, DDT and pirimiphos-methyl) in WHO tube bioassays, and concentration–response data were analysed with a Bayesian five-parameter logistic model to estimate LC50 values, quantify between- and within-laboratory variability, and assess the cross-insecticide rank correlation of site susceptibility. Testing laboratories are identified only by anonymised letter codes (A–P). The archive contains the four per-insecticide datasets, the Stan model and its compiled object, two R analysis scripts (LC50/variability estimation and Spearman correlation), and a README documenting the data format, folder structure and reproduction steps. Running the scripts reproduces the LC50 estimates, variability metrics, model checks and Spearman analysis reported in the associated paper.

Visit

doi.orgzenodo.org

Languages

Kenyan Sign Language

Tags

Insecticide ResistanceAnophelesanopheles gambiaekisumuinsecticide susceptibilityWHO tube bioassaydose-response relationshipbayesian analysisvector control

Licenses

Creative Commons Attribution 4.0 Internationalhttps://creativecommons.org/licenses/by/4.0/legalcode

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