Associations with common variants at known prostate cancer risk regions in African Americans (3,425 cases, 3,290 controls).

Domain:

healthcare

Record type:

dataset

Creator:

ChrGarWilSar

Host:

Risk allele/reference allele.

RAF, risk allele frequency in populations of European ancestry (EA) or HapMap CEU population, and in African Americans (AA) in this study. This is the allele associated with increased risk in previous GWAS.

Adjusted for age, study, the 1^st 10 eigenvalues and local ancestry at each risk locus.

Test of trend (1-d.f.).

Pairwise correlation between the index signal and the best marker in African Americans in CEU or JPT (where indicated) in 1000 Genomes Project (March 2010 release).

Index signal reported in Japanese. RAFs and r² based on Japanese data [11] or JPT in 1000 Genomes.

Imputed (Rsq≥0.87).

Best marker or index marker in AA is extremely rare or monomorphic in YRI.

r² of rs3760722 and rs2735839 in YRI is 0.24.

No SNP selected in stepwise procedure.

Estimated in HapMap JPT/CHB.

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