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Associations with risk variants at 8q24 in African Americans.

Domain:

healthcare

Record type:

paper
Creator:
ChrGarWilSar
Host:avatar
a

Risk regions as defined in [1], [2], [7], [10], [13].

b

Risk /reference alleles.

c

RAF, risk allele frequency in populations of European ancestry [1], [6 or HapMap CEU] and in African Americans (AA).

d

Adjusted for age, study, the 1st 10 eigenvalues and local ancestry for region 127.8–129.0 Mb (NCBI build 36).

e

Test of trend (1-d.f.).

f

From the multivariate model. OR adjusted for age, study, the 1st 10 eigenvalues, local ancestry and all other 8q24 risk variants.

g

The proportion of the variance explained by the other SNPs.

h

Imputed (Rsq≥0.76). rs445114 was not genotyped and could not be imputed [6].

i

SNPs kept in stepwise procedure if p<0.001.

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