The study examined the nexus between accounting software and financial irregularities using some selected deposit money banks in Nigeria. Specifically, the study examined the extent by which banks' fraud is detected, reduced and prevented by deployment of accounting software. Methodology: The study population comprised of 13 money deposit banks listed on the Nigeria stock exchange as at 31st December 2020. 70 respondents were sampled from 7 of the banks randomly selected from the entire population. Data was obtained using a well-structured questionnaire. Data collected were analyzed using descriptive statistics and analysis of variances.