The industry 4.0 technology has been in existence and development for a while now and it has been fully implemented by the “big player” manufacturing companies in the world. This paper provides an assessment of the key technologies and the low state of implementation of this technological transformation by industries in Africa and especially the SMEs. Therefore, the article gives a guide and conceptual roadmap with necessary resources, practices and strategies for the middle African companies to implement industry 4.0 in their organization and reap the benefits of this industrial and technological revolution.