The rapid growth of the digital economy is reshaping global economic structures and competition patterns. As part of the Belt and Road Initiative, the "Digital Silk Road" has strengthened China-Africa ties, making digital economy cooperation a key focus. This paper, from the perspectives of Global South and dependency theory, argues that China-Africa digital economic collaboration does not create dependence. Instead, it reduces Africa’s reliance on northern countries and improves its global standing. Unlike northern nations, China, as a leader in the digital economy, aims to empower the Global South and correct global inequalities through cooperation. The partnership has shown great potential, with achievements in digital infrastructure, e-commerce, and cultural industries. However, challenges remain at various levels: globally, geopolitical tensions rise; regionally, Africa faces a digital divide; nationally, there are internal resistances; and socially, issues like poverty and cultural clashes pose obstacles. Despite these challenges, the "Digital Silk Road" offers Africa the chance for economic diversification and industrial upgrading, paving the way for a more equitable, sustainable future. China and Africa must continue to collaborate, leveraging technology for mutual growth and a shared digital future.