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HE2AT Center RP2 Metadata Catalogue: Multi-System Biomarker Heat Analysis, Johannesburg

Domaine:

healthcareclimate
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Par
Éditeur:
Zenodo
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Metadata catalogue for the HE2AT Center Research Platform 2 (RP2) study: "Heat, Vulnerability, and the Body: Multi-System Biomarker Signatures of Temperature Exposure in Johannesburg Revealed Through Explainable Machine Learning" (Parker et al., 2026, target: Environmental Data Science).

This catalogue documents all harmonised datasets used in the analysis:

  • 14 Johannesburg clinical cohorts (2003–2021): 11,114 records, 27 biomarkers across 8 organ systems
  • ERA5 climate linkage: temperature at lags 0–30 days, heat indices, apparent temperature
  • GCRO socioeconomic linkage: ward-based nearest-neighbour matching (v4.0)
  • Heat Vulnerability Index (HVI): 3-component composite framework
  • Harmonisation protocols: ALCOA+ data quality framework, REDCap codebook, per-study QA reports

Clinical data are held under institutional data governance (University of the Witwatersrand HREC) and are not publicly available. The analysis pipeline is available at github.com

Funding: NIH U54 TW 012083 (HE2AT Center — Heat and Health in Africa).

Tags

metadata catalogueheat exposurebiomarkersclimate healthJohannesburgSouth Africasub-Saharan AfricavulnerabilityERA5HE2AT Center+2

Licenses

info:eu-repo/semantics/openAccessCreative Commons Attribution 4.0 Internationalhttps://creativecommons.org/licenses/by/4.0/legalcode

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