<i>De novo</i> emergence of artemisinin resistance under the baseline, status quo scenario.
Domaine:
healthcareType de record:
paper
Créateur:
RobTraAnyThu
Hôte:
In the baseline scenario, C580 is allowed to mutate to 580Y using a mutation rate that has been set to a previously calibrated pattern of artemisinin resistance in the presence of widespread ACT usage. The appearance of artemisinin resistance in model year 2021 appears to be stochastic with only minimal evidence of elevated frequency of the mutation and some cells with no occurrences. However, by model year 2036 the highest frequencies of artemisinin resistance correspond to areas with elevated to high transmission and high access to treatment. Burkina Faso administrative boundaries from the World Bank Group [19].
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