This article aims at the description and the contrastive analysis of suffixation, part of the affixal derivation, of Biali and German. Indeed, it describes two types of suffixation in Biali, namely: nominal suffixation and verbal suffixation. On the German side, it identifies and describes four types of suffixation which are the nominal, verbal, adjectival and adverbial suffixations. From the contrastive analysis of these different types of Biali and German suffixation, it notes that they have nominal and verbal suffixations in common. It points out that their differences are noticeable at the level of adjectival and adverbial suffixations, because these are only found in German and not in Biali.