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Supplementary Figure SF1 from Novel Paired Normal Prostate and Prostate Cancer Model Cell Systems Derived from African American Patients

Domaine:

healthcare

Type de record:

dataset
Créateur:
MirKeiRyaGau
Hôte:avatar

Figure S1: A) Results obtained from analyses of 15 autosomal short tandem repeat (STR) loci identify the male locus amelogenin. The profile of L/P4T is unique. No mouse DNA was detected for this sample. B) Karyotype of AP4T. Of 20 metaphases counted, 5 metaphases were analyzed. 3 metaphases were then karyotyped at 425 banding resolution. The image shows the 46,XY, male karyotype. Normal karyotype (male) within the limits of resolution attained. C) Cell growth and morphology under CR condition. Non-cancerous and cancerous cells derived from AP4 were expanded using CR condition. The images of 10x and 20x are from passage 1 and stained with H&E. The bottom image shows clonogenic growth of epithelial cells and J2 fibroblasts after 4 days and 7 days of culture. On day 7, clonogenic epithelial cells are marked in yellow arrow and J2 fibroblasts in cyan blue arrow.

Tags

CancerMolecular and Cellular BiologyTherapeutic Research and DevelopmentClinical Research and TrialsMethods and TechnologyGenitourinary CancersProstate cancerPreclinical ModelsIn vitro models of cancerChemotherapy+3

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CC BY

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